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Haplotype-independent co-stimulation of IL-10 secretion by SDF-1/CXCL12 proceeds via AP-1 binding to the human IL-10 promoter
Co-stimulation by the chemokine, SDF-1/CXCL12, has been shown to increase the amount of IL-10 secreted by TCR-stimulated human T cells, however, the molecular mechanisms of this response are unknown. Knowledge of this signaling pathway may be useful since extensive evidence indicates that deficient...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905171/ https://ncbi.nlm.nih.gov/pubmed/17237407 |
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