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Secreted CXCL12 (SDF-1) Forms Dimers under Physiologic Conditions
Chemokine CXCL12 signaling through receptors CXCR4 and CXCR7 has essential functions in development and underlies diseases including cancer, atherosclerosis, and autoimmunity. Chemokines may form homodimers that regulate receptor binding and signaling, but previous studies with synthetic CXCL12 have...
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Publicado no: | Biochem J |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4419379/ https://ncbi.nlm.nih.gov/pubmed/22142194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111341 |
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