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Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance

Chemically modified nucleic acids (CNAs) are widely explored as antisense oligonucleotide or small interfering RNA (siRNA) candidates for therapeutic applications. CNAs are also of interest in diagnostics, high-throughput genomics and target validation, nanotechnology and as model systems in investi...

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Detalhes bibliográficos
Main Authors: Egli, Martin, Pallan, Pradeep S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905155/
https://ncbi.nlm.nih.gov/pubmed/20087997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbdv.200900177
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