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How Pancreatic β-Cells Discriminate Long and Short Timescale cAMP Signals

The translocation of catalytic protein kinase A (cPKA) in response to cyclic-adenosine mono-phosphate (cAMP) depends on the pattern of stimulus applied to the cell. Experiments with IBMX have shown that 1), sustained cAMP elevation is more effective than oscillations of cAMP at getting cPKA into the...

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Autors principals: Peercy, Bradford E., Sherman, Arthur S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905120/
https://ncbi.nlm.nih.gov/pubmed/20643057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.043
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