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Regulation of microRNA-375 by cAMP in Pancreatic β-Cells

MicroRNA-375 (miR-375) is necessary for proper formation of pancreatic islets in vertebrates and is necessary for the development of β-cells in mice, but regulation of miR-375 in these cells is poorly understood. Here, we show that miR-375 is transcriptionally repressed by the cAMP-protein kinase A...

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Autors principals: Keller, David M., Clark, Elizabeth A., Goodman, Richard H.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355542/
https://ncbi.nlm.nih.gov/pubmed/22539037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1205
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