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TGF-β and ‘Adaptive’ Foxp3(+) Regulatory T cells
In naïve T cells transforming growth factor-beta (TGF-β) induces Foxp3, a transcription factor essential for programming and developing T regulatory cells (Treg cells). This finding reveals a physiological factor which can turn on the Foxp3 gene and establishes an experimental approach to induce ant...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905060/ https://ncbi.nlm.nih.gov/pubmed/19648226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjp004 |
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