Bevacizumab-Induced Tumor Vessel Remodeling in Rhabdomyosarcoma Xenografts Increases the Effectiveness of Adjuvant Ionizing Radiation

PURPOSE: Inhibition of VEGF may effect transient “normalization” of tumor vasculature by pruning immature vessels, resulting in improved tumor perfusion and oxygenation. This may improve the efficacy of adjuvant ionizing radiation (IR). We tested this hypothesis using bevacizumab, an anti-VEGF antib...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Myers, Adrianne L., Williams, Regan F., Ng, Cathy Y., Hartwich, Joseph E., Davidoff, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904306/
https://ncbi.nlm.nih.gov/pubmed/20620299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2010.02.068
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky