Improved intratumoral oxygenation through vascular normalization increases glioma sensitivity to ionizing radiation

PURPOSE: Ionizing radiation, an important component of glioma therapy, is critically dependent on tumor oxygenation. However, gliomas are notable for areas of necrosis and hypoxia, which foster radioresistance. We hypothesized that pharmacologic manipulation of the typically dysfunctional tumor vasc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McGee, Mackenzie C., Hamner, J. Blair, Williams, Regan F., Rosati, Shannon F., Sims, Thomas L., Ng, Catherine Y., Gaber, M. Waleed, Calabrese, Christopher, Wu, Jianrong, Nathwani, Amit C., Duntsch, Christopher, Merchant, Thomas E., Davidoff, Andrew M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846307/
https://ncbi.nlm.nih.gov/pubmed/20338480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.12.010
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