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Ceramide modulates HERG potassium channel gating by translocation into lipid rafts

Human ether-à-go-go-related gene (HERG) potassium channels play an important role in cardiac action potential repolarization, and HERG dysfunction can cause cardiac arrhythmias. However, recent evidence suggests a role for HERG in the proliferation and progression of multiple types of cancers, makin...

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Detalhes bibliográficos
Main Authors: Ganapathi, Sindura B., Fox, Todd E., Kester, Mark, Elmslie, Keith S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904259/
https://ncbi.nlm.nih.gov/pubmed/20375276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00462.2009
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