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The role of spermidine/spermine N(1)-acetyltransferase in endotoxin-induced acute kidney injury

The expression of catabolic enzymes spermidine/spermine N(1)-acetyltransferase (SSAT) and spermine oxidase (SMO) increases after ischemic reperfusion injury. We hypothesized that polyamine catabolism is upregulated and that this increase in catabolic response contributes to tissue damage in endotoxi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zahedi, Kamyar, Barone, Sharon, Kramer, Debora L., Amlal, Hassane, Alhonen, Leena, Jänne, Juhani, Porter, Carl W., Soleimani, Manoocher
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904252/
https://ncbi.nlm.nih.gov/pubmed/20392931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00512.2009
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