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Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine
Precursors of the peptide hormone gastrin stimulate proliferation in the colorectal mucosa and promote the development of colorectal carcinoma. Gastrins bind two ferric ions selectively and with high affinity, and the biological activity of glycine-extended gastrin (Ggly) in vitro is dependent on th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904120/ https://ncbi.nlm.nih.gov/pubmed/20395538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00046.2010 |
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