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Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth

Precursors of the hormone gastrin, progastrin and glycine-extended gastrin (G-gly), have been detected in colorectal polyps and tumours, and in the blood of patients with colorectal cancer (CRC), while their expression is lower in healthy subjects. The surface glycoproteins CD133 and CD44 have been...

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Detalhes bibliográficos
Main Authors: FERRAND, Audrey, SANDRIN, Mauro S., SHULKES, Arthur, BALDWIN, Graham S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692632/
https://ncbi.nlm.nih.gov/pubmed/19321126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2009.01.004
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