Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and β-cell proliferation in the developing mouse pancreas

Glial cell line-derived neurotrophic factor (GDNF) is a factor produced by glial cells that is required for the development of the enteric nervous system. In transgenic mice that overexpress GDNF in the pancreas, GDNF has been shown to enhance β-cell mass and improve glucose control, but the transcr...

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Detalhes bibliográficos
Main Authors: Mwangi, Simon M., Usta, Yousef, Raja, Shreya M., Anitha, Mallappa, Chandrasekharan, Bindu, Parsadanian, Alexander, Sitaraman, Shanthi V., Srinivasan, Shanthi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904114/
https://ncbi.nlm.nih.gov/pubmed/20448145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00096.2010
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