Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and β-cell proliferation in the developing mouse pancreas

Glial cell line-derived neurotrophic factor (GDNF) is a factor produced by glial cells that is required for the development of the enteric nervous system. In transgenic mice that overexpress GDNF in the pancreas, GDNF has been shown to enhance β-cell mass and improve glucose control, but the transcr...

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מידע ביבליוגרפי
Main Authors: Mwangi, Simon M., Usta, Yousef, Raja, Shreya M., Anitha, Mallappa, Chandrasekharan, Bindu, Parsadanian, Alexander, Sitaraman, Shanthi V., Srinivasan, Shanthi
פורמט: Artigo
שפה:Inglês
יצא לאור: American Physiological Society 2010
נושאים:
Hormones and Signaling
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904114/
https://ncbi.nlm.nih.gov/pubmed/20448145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00096.2010
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