GDNF rescues hyperglycemia-induced diabetic enteric neuropathy through activation of the PI3K/Akt pathway

Diabetes can result in loss of enteric neurons and subsequent gastrointestinal complications. The mechanism of enteric neuronal loss in diabetes is not known. We examined the effects of hyperglycemia on enteric neuronal survival and the effects of glial cell line–derived neurotrophic factor (GDNF) o...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anitha, Mallappa, Gondha, Chetan, Sutliff, Roy, Parsadanian, Alexander, Mwangi, Simon, Sitaraman, Shanthi V., Srinivasan, Shanthi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2006
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1359053/
https://ncbi.nlm.nih.gov/pubmed/16453021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26295
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