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Colonic motor dysfunction in human diabetes is associated with enteric neuronal loss and increased oxidative stress

BACKGROUND: Gastrointestinal dysfunction is very common in diabetic patients. We assessed the changes in the colonic enteric nervous system using colectomy specimens and intestinal biopsies from diabetic subjects and age-matched controls. METHODS: In control and diabetic colons, we determined the to...

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Detalhes bibliográficos
Main Authors: Chandrasekharan, Bindu, Anitha, Mallappa, Blatt, Richard, Shahnavaz, Nikrad, Kooby, David, Staley, Charles, Mwangi, Simon, Jones, Dean P, Sitaraman, Shanthi V., Srinivasan, Shanthi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020997/
https://ncbi.nlm.nih.gov/pubmed/20939847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2010.01611.x
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