Glial Cell Line-Derived Neurotrophic Factor increases beta cell mass and improves glucose tolerance

BACKGROUND & AIMS: Pancreatic β-cell mass increases in response to increased demand for insulin, but the factors involved are largely unknown. Glial cell line-derived neurotrophic factor (GDNF) is a growth factor that plays a role in the development and survival of the enteric nervous system. We...

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Main Authors: Mwangi, Simon, Anitha, M., Mallikarjun, Chaithanya, Ding, Xiaokun, Hara, Manami, Parsadanian, Alexander, Larsen, Christian P., Thule, Peter, Sitaraman, Shanthi V., Anania, Frank, Srinivasan, Shanthi
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725148/
https://ncbi.nlm.nih.gov/pubmed/18241861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.12.033
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