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Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery
Myosin phosphatase target subunit 1 (MYPT1) is the regulatory subunit of myosin light chain phosphatase (MLCP). It plays a critical role in vasodilatation induced by cGMP-elevating agents such as nitric oxide (NO). The present study was performed to determine the role of MYPT1 in the development of...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904097/ https://ncbi.nlm.nih.gov/pubmed/20418385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00340.2009 |
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