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Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response
The integrity of DNA is constantly challenged throughout the life of a cell by both endogenous and exogenous stresses. A well-organized rapid damage response and proficient DNA repair, therefore, becomes critically important for maintaining genomic stability and cell survival. When DNA is damaged, t...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904079/ https://ncbi.nlm.nih.gov/pubmed/20460517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4244 |
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