Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response

The integrity of DNA is constantly challenged throughout the life of a cell by both endogenous and exogenous stresses. A well-organized rapid damage response and proficient DNA repair, therefore, becomes critically important for maintaining genomic stability and cell survival. When DNA is damaged, t...

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Bibliografski detalji
Glavni autori: Cha, Hyukjin, Lowe, Julie M., Li, Henghong, Lee, Ji-Seon, Belova, Galina I., Bulavin, Dmitry V., Fornace, Albert J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904079/
https://ncbi.nlm.nih.gov/pubmed/20460517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4244
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