Nuclear Factor-κB (NF-κB) Is a Novel Positive Transcriptional Regulator of the Oncogenic Wip1 Phosphatase

The nuclear factor-κB (NF-κB) family of transcription factors plays a key role in inflammation and augments the initiation, promotion, and progression of cancer.NF-κB activation generally leads to transcriptional enhancement of genes important in cell survival and cell growth, which is exploited in...

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Bibliographic Details
Main Authors: Lowe, Julie M., Cha, Hyukjin, Yang, Qian, Fornace, Albert J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820753/
https://ncbi.nlm.nih.gov/pubmed/20007970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.034579
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