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Distinct gene expression profiles characterize cellular responses to palmitate and oleate

Obese individuals are both insulin resistant and have high levels of circulating free fatty acids (FFAs). In cell culture, saturated but not unsaturated fatty acids induce endoplasmic reticulum (ER) stress. We hypothesized that chronic exposure to low dose fatty acids would significantly attenuate t...

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Detalhes bibliográficos
Main Authors: Das, Swapan K., Mondal, Ashis K., Elbein, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903813/
https://ncbi.nlm.nih.gov/pubmed/20410017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M004275
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