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Allelic expression imbalance screening of genes in chromosome 1q21–24 region to identify functional variants for Type 2 diabetes susceptibility

Type 2 diabetes (T2D)-associated SNPs are more likely to be expression quantitative trait loci (eQTLs). The allelic expression imbalance (AEI) analysis is the measure of relative expression between two allelic transcripts and is the most sensitive measurement to detect cis-regulatory effects. We per...

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Detalhes bibliográficos
Main Authors: Mondal, Ashis K., Sharma, Neeraj K., Elbein, Steven C., Das, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727020/
https://ncbi.nlm.nih.gov/pubmed/23673729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00048.2013
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