Carregant...
Exploiting Enzyme Plasticity in Virtual Screening: High Efficiency Inhibitors of Glutamate Racemase
[Image: see text] Glutamate racemase is an attractive antimicrobial drug target. Virtual screening using a transition-state conformation of the enzyme resulted in the discovery of several μM competitive inhibitors, dissimilar from current amino acid-like inhibitors, providing novel scaffolds for dru...
Guardat en:
| Autors principals: | , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2009
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903749/ https://ncbi.nlm.nih.gov/pubmed/20634968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml900005b |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|