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The Discovery and Application of Gene Fusions in Prostate Cancer

Chromosomal rearrangements play a causal role in hematological and mesenchymal malignancies. Importantly, the resulting gene fusions can serve as specific therapeutic targets, as exemplified by the development of imatinib (Gleevec), which specifically inhibits the BCR-ABL gene fusion product that de...

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Sonraí Bibleagrafaíochta
Main Authors: Morris, David S., Tomlins, Scott A., Montie, James E., Chinnaiyan, Arul M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903741/
https://ncbi.nlm.nih.gov/pubmed/18422767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2008.07665.x
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