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The Discovery and Application of Gene Fusions in Prostate Cancer
Chromosomal rearrangements play a causal role in hematological and mesenchymal malignancies. Importantly, the resulting gene fusions can serve as specific therapeutic targets, as exemplified by the development of imatinib (Gleevec), which specifically inhibits the BCR-ABL gene fusion product that de...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903741/ https://ncbi.nlm.nih.gov/pubmed/18422767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-410X.2008.07665.x |
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