Using the realized relationship matrix to disentangle confounding factors for the estimation of genetic variance components of complex traits

BACKGROUND: In the analysis of complex traits, genetic effects can be confounded with non-genetic effects, especially when using full-sib families. Dominance and epistatic effects are typically confounded with additive genetic and non-genetic effects. This confounding may cause the estimated genetic...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lee, Sang Hong, Goddard, Michael E, Visscher, Peter M, van der Werf, Julius HJ
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903499/
https://ncbi.nlm.nih.gov/pubmed/20546624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-42-22
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi