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p53-dependent senescence delays Eμ-myc-induced B-cell lymphomagenesis
The effect of p53-dependent cell-cycle arrest and senescence on Eμ-myc-induced B-cell lymphoma development remains controversial. To address this question, we crossed Eμ-myc mice with the p53(515C) mutant mouse, encoding the mutant p53R172P protein that retains the ability to activate the cell-cycle...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903442/ https://ncbi.nlm.nih.gov/pubmed/19935700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.423 |
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