Protein Kinase C Isoforms ζ and ι Mediate Collagenase Expression and Cartilage Destruction via STAT3- and ERK-dependent c-fos Induction

The protein kinase C (PKC) signaling pathway is a major regulator of cellular functions and is implicated in pathologies involving extracellular matrix remodeling. Inflammatory joint disease is characterized by excessive extracellular matrix catabolism, and here we assess the role of PKC in the indu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Litherland, Gary J., Elias, Martina S., Hui, Wang, Macdonald, Christopher D., Catterall, Jonathon B., Barter, Matt J., Farren, Matthew J., Jefferson, Matthew, Rowan, Andrew D.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2010
נושאים:
Glycobiology and Extracellular Matrices
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903406/
https://ncbi.nlm.nih.gov/pubmed/20463008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.120121
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים