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Pharmacogenetic Predictors of Adverse Events and Response to Chemotherapy in Metastatic Colorectal Cancer: Results From North American Gastrointestinal Intergroup Trial N9741

PURPOSE: With three available chemotherapy drugs for advanced colorectal cancer (CRC), response rate (RR) and survival outcomes have improved with associated morbidity, accentuating the need for tools to select optimal individualized treatment. Pharmacogenetics identifies the likelihood of adverse e...

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Main Authors: McLeod, Howard L., Sargent, Daniel J., Marsh, Sharon, Green, Erin M., King, Cristi R., Fuchs, Charles S., Ramanathan, Ramesh K., Williamson, Stephen K., Findlay, Brian P., Thibodeau, Stephen N., Grothey, Axel, Morton, Roscoe F., Goldberg, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903324/
https://ncbi.nlm.nih.gov/pubmed/20530282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.21.7943
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