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Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122
miR-122 is a liver-specific microRNA that positively regulates hepatitis C virus (HCV) RNA abundance and is essential for production of infectious HCV. Using a genetic approach, we show that its ability to enhance yields of infectious virus is dependent upon two miR-122-binding sites near the 5′ end...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903297/ https://ncbi.nlm.nih.gov/pubmed/20427538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00417-10 |
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