Rotavirus Nonstructural Protein 1 Suppresses Virus-Induced Cellular Apoptosis To Facilitate Viral Growth by Activating the Cell Survival Pathways during Early Stages of Infection

Following virus infection, one of the cellular responses to limit the virus spread is induction of apoptosis. In the present study, we report role of rotavirus nonstructural protein 1 (NSP1) in regulating apoptosis by activating prosurvival pathways such as phosphatidylinositol 3-kinase (PI3K)/Akt a...

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Hlavní autoři: Bagchi, Parikshit, Dutta, Dipanjan, Chattopadhyay, Shiladitya, Mukherjee, Anupam, Halder, Umesh Chandra, Sarkar, Sagartirtha, Kobayashi, Nobumichi, Komoto, Satoshi, Taniguchi, Koki, Chawla-Sarkar, Mamta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903281/
https://ncbi.nlm.nih.gov/pubmed/20392855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00225-10
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