Rotaviral Enterotoxin Nonstructural Protein 4 Targets Mitochondria for Activation of Apoptosis during Infection

Viruses have evolved to encode multifunctional proteins to control the intricate cellular signaling pathways by using very few viral proteins. Rotavirus is known to express six nonstructural and six structural proteins. Among them, NSP4 is the enterotoxin, known to disrupt cellular Ca(2+) homeostasi...

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Autors principals: Bhowmick, Rahul, Halder, Umesh Chandra, Chattopadhyay, Shiladitya, Chanda, Shampa, Nandi, Satabdi, Bagchi, Parikshit, Nayak, Mukti Kant, Chakrabarti, Oishee, Kobayashi, Nobumichi, Chawla-Sarkar, Mamta
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471681/
https://ncbi.nlm.nih.gov/pubmed/22888003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369595
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