Rotaviral Enterotoxin Nonstructural Protein 4 Targets Mitochondria for Activation of Apoptosis during Infection

Viruses have evolved to encode multifunctional proteins to control the intricate cellular signaling pathways by using very few viral proteins. Rotavirus is known to express six nonstructural and six structural proteins. Among them, NSP4 is the enterotoxin, known to disrupt cellular Ca(2+) homeostasi...

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Detalhes bibliográficos
Main Authors: Bhowmick, Rahul, Halder, Umesh Chandra, Chattopadhyay, Shiladitya, Chanda, Shampa, Nandi, Satabdi, Bagchi, Parikshit, Nayak, Mukti Kant, Chakrabarti, Oishee, Kobayashi, Nobumichi, Chawla-Sarkar, Mamta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471681/
https://ncbi.nlm.nih.gov/pubmed/22888003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369595
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