Rotavirus Nonstructural Protein 1 Suppresses Virus-Induced Cellular Apoptosis To Facilitate Viral Growth by Activating the Cell Survival Pathways during Early Stages of Infection

Following virus infection, one of the cellular responses to limit the virus spread is induction of apoptosis. In the present study, we report role of rotavirus nonstructural protein 1 (NSP1) in regulating apoptosis by activating prosurvival pathways such as phosphatidylinositol 3-kinase (PI3K)/Akt a...

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Detalhes bibliográficos
Main Authors: Bagchi, Parikshit, Dutta, Dipanjan, Chattopadhyay, Shiladitya, Mukherjee, Anupam, Halder, Umesh Chandra, Sarkar, Sagartirtha, Kobayashi, Nobumichi, Komoto, Satoshi, Taniguchi, Koki, Chawla-Sarkar, Mamta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903281/
https://ncbi.nlm.nih.gov/pubmed/20392855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00225-10
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