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Viral Entry Inhibitors Targeted to the Membrane Site of Action
The fusion of enveloped viruses with the host cell is driven by specialized fusion proteins to initiate infection. The “class I” fusion proteins harbor two regions, typically two heptad repeat (HR) domains, which are central to the complex conformational changes leading to fusion: the first heptad r...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology (ASM)
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903269/ https://ncbi.nlm.nih.gov/pubmed/20357085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00135-10 |
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