Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by preventing formation of the fusoge...

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Bibliografiska uppgifter
Huvudupphovsmän: Porotto, Matteo, Rockx, Barry, Yokoyama, Christine C., Talekar, Aparna, DeVito, Ilaria, Palermo, Laura M., Liu, Jie, Cortese, Riccardo, Lu, Min, Feldmann, Heinz, Pessi, Antonello, Moscona, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965769/
https://ncbi.nlm.nih.gov/pubmed/21060819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001168
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