Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by preventing formation of the fusoge...

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Detalhes bibliográficos
Main Authors: Porotto, Matteo, Rockx, Barry, Yokoyama, Christine C., Talekar, Aparna, DeVito, Ilaria, Palermo, Laura M., Liu, Jie, Cortese, Riccardo, Lu, Min, Feldmann, Heinz, Pessi, Antonello, Moscona, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965769/
https://ncbi.nlm.nih.gov/pubmed/21060819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001168
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