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Suppression of a Morphogenic Mutant in Rous Sarcoma Virus Capsid Protein by a Second-Site Mutation: a Cryoelectron Tomography Study

Retrovirus assembly is driven by polymerization of the Gag polyprotein as nascent virions bud from host cells. Gag is then processed proteolytically, releasing the capsid protein (CA) to assemble de novo inside maturing virions. CA has N-terminal and C-terminal domains (NTDs and CTDs, respectively)...

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Hlavní autoři: Butan, Carmen, Lokhandwala, Parvez M., Purdy, John G., Cardone, Giovanni, Craven, Rebecca C., Steven, Alasdair C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903260/
https://ncbi.nlm.nih.gov/pubmed/20427531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00207-10
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