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Suppression of a Morphogenic Mutant in Rous Sarcoma Virus Capsid Protein by a Second-Site Mutation: a Cryoelectron Tomography Study

Retrovirus assembly is driven by polymerization of the Gag polyprotein as nascent virions bud from host cells. Gag is then processed proteolytically, releasing the capsid protein (CA) to assemble de novo inside maturing virions. CA has N-terminal and C-terminal domains (NTDs and CTDs, respectively)...

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Bibliografische gegevens
Hoofdauteurs: Butan, Carmen, Lokhandwala, Parvez M., Purdy, John G., Cardone, Giovanni, Craven, Rebecca C., Steven, Alasdair C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903260/
https://ncbi.nlm.nih.gov/pubmed/20427531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00207-10
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