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Suppression of a Morphogenic Mutant in Rous Sarcoma Virus Capsid Protein by a Second-Site Mutation: a Cryoelectron Tomography Study

Retrovirus assembly is driven by polymerization of the Gag polyprotein as nascent virions bud from host cells. Gag is then processed proteolytically, releasing the capsid protein (CA) to assemble de novo inside maturing virions. CA has N-terminal and C-terminal domains (NTDs and CTDs, respectively)...

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Detalhes bibliográficos
Main Authors: Butan, Carmen, Lokhandwala, Parvez M., Purdy, John G., Cardone, Giovanni, Craven, Rebecca C., Steven, Alasdair C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903260/
https://ncbi.nlm.nih.gov/pubmed/20427531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00207-10
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