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Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference

We compared HEp-2-derived cells cured of persistent poliovirus infection by RNA interference (RNAi) with parental cells, to investigate possible changes in the efficiency of RNAi. Lower levels of poliovirus replication were observed in cured cells, possibly facilitating virus silencing by antiviral...

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Bibliografische gegevens
Hoofdauteurs: Pelletier, Isabelle, Saulnier, Aure, Brisac, Cynthia, Jegouic, Sophie, Vabret, Nicolas, Tangy, Frédéric, Blondel, Bruno, Colbère-Garapin, Florence
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903240/
https://ncbi.nlm.nih.gov/pubmed/20392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02060-09
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