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Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference

We compared HEp-2-derived cells cured of persistent poliovirus infection by RNA interference (RNAi) with parental cells, to investigate possible changes in the efficiency of RNAi. Lower levels of poliovirus replication were observed in cured cells, possibly facilitating virus silencing by antiviral...

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Bibliografski detalji
Glavni autori: Pelletier, Isabelle, Saulnier, Aure, Brisac, Cynthia, Jegouic, Sophie, Vabret, Nicolas, Tangy, Frédéric, Blondel, Bruno, Colbère-Garapin, Florence
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903240/
https://ncbi.nlm.nih.gov/pubmed/20392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02060-09
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