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Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference

We compared HEp-2-derived cells cured of persistent poliovirus infection by RNA interference (RNAi) with parental cells, to investigate possible changes in the efficiency of RNAi. Lower levels of poliovirus replication were observed in cured cells, possibly facilitating virus silencing by antiviral...

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Dettagli Bibliografici
Autori principali: Pelletier, Isabelle, Saulnier, Aure, Brisac, Cynthia, Jegouic, Sophie, Vabret, Nicolas, Tangy, Frédéric, Blondel, Bruno, Colbère-Garapin, Florence
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903240/
https://ncbi.nlm.nih.gov/pubmed/20392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02060-09
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