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Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference

We compared HEp-2-derived cells cured of persistent poliovirus infection by RNA interference (RNAi) with parental cells, to investigate possible changes in the efficiency of RNAi. Lower levels of poliovirus replication were observed in cured cells, possibly facilitating virus silencing by antiviral...

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Main Authors: Pelletier, Isabelle, Saulnier, Aure, Brisac, Cynthia, Jegouic, Sophie, Vabret, Nicolas, Tangy, Frédéric, Blondel, Bruno, Colbère-Garapin, Florence
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903240/
https://ncbi.nlm.nih.gov/pubmed/20392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02060-09
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