Enhanced Gene Silencing in Cells Cured of Persistent Virus Infection by RNA Interference

We compared HEp-2-derived cells cured of persistent poliovirus infection by RNA interference (RNAi) with parental cells, to investigate possible changes in the efficiency of RNAi. Lower levels of poliovirus replication were observed in cured cells, possibly facilitating virus silencing by antiviral...

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Hlavní autoři: Pelletier, Isabelle, Saulnier, Aure, Brisac, Cynthia, Jegouic, Sophie, Vabret, Nicolas, Tangy, Frédéric, Blondel, Bruno, Colbère-Garapin, Florence
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903240/
https://ncbi.nlm.nih.gov/pubmed/20392843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02060-09
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