CYP2C9 and VKORC1 Genotypes in Puerto Ricans: A Case for Admixture-Matching in Clinical Pharmacogenetic Studies

BACKGROUNDS: Admixture is of great relevance to the clinical application of pharmacogenetics and personalized medicine, but unfortunately these studies have been scarce in Puerto Ricans. Besides, allele frequencies for clinically relevant genetic markers in warfarin response (i.e., CYP2C9 and VKORC1...

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Detalhes bibliográficos
Main Authors: Villagra, David, Duconge, Jorge, Windemuth, Andreas, Cadilla, Carmen L, Kocherla, Mohan, Gorowski, Krystyna, Bogaard, Kali, Renta, Jessica Y, Cruz, Irelys A, Mirabal, Sara, Seip, Richard L, Ruaño, Gualberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903218/
https://ncbi.nlm.nih.gov/pubmed/20488169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2010.05.021
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