CYP2C9 and VKORC1 Genotypes in Puerto Ricans: A Case for Admixture-Matching in Clinical Pharmacogenetic Studies

BACKGROUNDS: Admixture is of great relevance to the clinical application of pharmacogenetics and personalized medicine, but unfortunately these studies have been scarce in Puerto Ricans. Besides, allele frequencies for clinically relevant genetic markers in warfarin response (i.e., CYP2C9 and VKORC1...

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Hauptverfasser: Villagra, David, Duconge, Jorge, Windemuth, Andreas, Cadilla, Carmen L, Kocherla, Mohan, Gorowski, Krystyna, Bogaard, Kali, Renta, Jessica Y, Cruz, Irelys A, Mirabal, Sara, Seip, Richard L, Ruaño, Gualberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903218/
https://ncbi.nlm.nih.gov/pubmed/20488169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2010.05.021
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