CYP2C9 and VKORC1 Genotypes in Puerto Ricans: A Case for Admixture-Matching in Clinical Pharmacogenetic Studies

BACKGROUNDS: Admixture is of great relevance to the clinical application of pharmacogenetics and personalized medicine, but unfortunately these studies have been scarce in Puerto Ricans. Besides, allele frequencies for clinically relevant genetic markers in warfarin response (i.e., CYP2C9 and VKORC1...

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Autores principales: Villagra, David, Duconge, Jorge, Windemuth, Andreas, Cadilla, Carmen L, Kocherla, Mohan, Gorowski, Krystyna, Bogaard, Kali, Renta, Jessica Y, Cruz, Irelys A, Mirabal, Sara, Seip, Richard L, Ruaño, Gualberto
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903218/
https://ncbi.nlm.nih.gov/pubmed/20488169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2010.05.021
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