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Novel macromolecular inhibitors of human immunodeficiency virus-1 protease
An intracellularly expressed defective human immunodeficiency virus type-1 (HIV-1) protease (PR) monomer could function as a dominant-negative inhibitor of the enzyme that requires dimerization for activity. Based on in silico studies, two mutant PRs harboring hydrophilic mutations, capable of formi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902902/ https://ncbi.nlm.nih.gov/pubmed/18480092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzn022 |
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