Amino Acid Preferences for a Critical Substrate Binding Subsite of Retroviral Proteases in Type 1 Cleavage Sites

The specificities of the proteases of 11 retroviruses representing each of the seven genera of the family Retroviridae were studied using a series of oligopeptides with amino acid substitutions in the P2 position of a naturally occurring type 1 cleavage site (Val-Ser-Gln-Asn-Tyr↓Pro-Ile-Val-Gln; the...

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Detalhes bibliográficos
Main Authors: Bagossi, Péter, Sperka, Tamás, Fehér, Anita, Kádas, János, Zahuczky, Gábor, Miklóssy, Gabriella, Boross, Péter, Tözsér, József
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061542/
https://ncbi.nlm.nih.gov/pubmed/15767422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4213-4218.2005
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