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The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis

OBJECTIVES: Increased bone marrow iron levels in patients with haematological malignancies is an independent risk factor for developing invasive pulmonary aspergillosis (IPA), suggesting an important role for iron uptake in the pathogenesis of IPA. We sought to determine the potential for combinatio...

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Detalhes bibliográficos
Main Authors: Ibrahim, Ashraf S., Gebremariam, Teclegiorgis, French, Samuel W., Edwards, John E., Spellberg, Brad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902852/
https://ncbi.nlm.nih.gov/pubmed/19942619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp426
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