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Real-time monitoring of nucleic acid ligation in homogenous solutions using molecular beacons

Nucleic acids ligation is a vital process in the repair, replication and recombination of nucleic acids. Traditionally, it is assayed by denatured gel electrophoresis and autoradiography, which are not sensitive, and are complex and discontinuous. Here we report a new approach for ligation monitorin...

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Hlavní autoři: Tang, Zhiwen, Wang, Kemin, Tan, Weihong, Li, Jun, Liu, Lingfeng, Guo, Qiuping, Meng, Xiangxian, Ma, Changbei, Huang, Shasheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC290283/
https://ncbi.nlm.nih.gov/pubmed/14627838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng146
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