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Real-time monitoring of nucleic acid ligation in homogenous solutions using molecular beacons

Nucleic acids ligation is a vital process in the repair, replication and recombination of nucleic acids. Traditionally, it is assayed by denatured gel electrophoresis and autoradiography, which are not sensitive, and are complex and discontinuous. Here we report a new approach for ligation monitorin...

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Main Authors: Tang, Zhiwen, Wang, Kemin, Tan, Weihong, Li, Jun, Liu, Lingfeng, Guo, Qiuping, Meng, Xiangxian, Ma, Changbei, Huang, Shasheng
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC290283/
https://ncbi.nlm.nih.gov/pubmed/14627838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng146
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