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Interferon-γ Primes Intact Human Coronary Arteries and Cultured Coronary Smooth Muscle Cells to dsRNA and self-RNA Induced Inflammatory Responses by Upregulating TLR3 and MDA5

Atherosclerosis of native coronary arteries and graft arteriosclerosis in transplanted hearts are characterized by activation of innate and adaptive immune responses. Nucleic acids generated by infections or cell death have been detected within arteriosclerotic lesions and it is known that microbial...

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Hlavní autoři: Ahmad, Usman, Ali, Rahmat, Lebastchi, Amir H., Qin, Lingfeng, Lo, Sheng-fu L., Yakimov, Alexander O., Khan, Salman F., Choy, Jonathan C., Geirsson, Arnar, Pober, Jordan S., Tellides, George
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902797/
https://ncbi.nlm.nih.gov/pubmed/20562257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902283
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