Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside

A ribose residue inserted between the 3′-OH of one nucleotide and the 5′-phosphate group of the next nucleotide, functions as a site-specific cleavage site within DNA. This extra ribose does not interrupt helix formation and it protects duplex DNA against cleavage by restriction enzymes. Cleavage ca...

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Detalhes bibliográficos
Main Authors: Nauwelaerts, Koen, Vastmans, Karen, Froeyen, Matheus, Kempeneers, Veerle, Rozenski, Jef, Rosemeyer, Helmut, Van Aerschot, Arthur, Busson, Roger, Lacey, Jeffrey C., Efimtseva, Ekaterina, Mikhailov, Sergey, Lescrinier, Eveline, Herdewijn, Piet
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC290278/
https://ncbi.nlm.nih.gov/pubmed/14627809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg911
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