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Cleavage of DNA without loss of genetic information by incorporation of a disaccharide nucleoside
A ribose residue inserted between the 3′-OH of one nucleotide and the 5′-phosphate group of the next nucleotide, functions as a site-specific cleavage site within DNA. This extra ribose does not interrupt helix formation and it protects duplex DNA against cleavage by restriction enzymes. Cleavage ca...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC290278/ https://ncbi.nlm.nih.gov/pubmed/14627809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg911 |
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